Enzalutamide Improves Survival in Patients with Metastatic

It's no secret to oncologists that Xtandi (Xtandi) is not only a potent drug in combating prostate cancer but also an expensive one. With an average US wholesale price of $88 per capsule in 2015, Xtandi cost can add up to $129,000 in a year's time for just one patient.

 

The drug BDENZA (Xtandi) is an analogue (generic) of Xtandi.

 

The active substance Xtandi is a non-steroidal, synthetic, anti-androgen that blocks the appearance of sex hormones inside the body.

 

Indications for use
 

The drug Bdenza enzalutamide is prescribed to men by an oncologist after diagnosis, in the presence of a prostate tumor (metostatic, castration-resistant cancer) at a late stage of development, not amenable to resectability or treatment with testosterone-lowering medications.

The mechanism of action of the drug

 

A malignant formation (tumor) occurs in the prostate gland, in the cells of which there are receptors that come into contact with androgens, which contribute to their rapid growth. The enlargement of the tumor is fueled by testosterone, the male sex hormone.

The drug acts as an inhibitor of androgens, reducing their amount, which reduces the activity of the growth of a malignant tumor and reduces the size of the formation itself.

Dosage recommendations

The daily dose recommended by the manufacturer is to take 4 tablets of 40 mg, that is, 160 mg per day. Capsules are taken orally, before or after meals, with plenty of water. The optimal course and dose of the drug is prescribed by the attending physician, based on the patient's clinical history.

Interaction with other medications

Before prescribing anticancer therapy, you must inform your doctor about all medications that you have been prescribed for other diseases, as some are not compatible with BDENZA.

Caution is needed in the simultaneous administration of antibiotic agents, antidepressants, bronchodilators, hormonal pills, insulin-containing or other drugs for diabetes, steroids, and medicines for mental illnesses with Xtandi.

 

Contraindications

The Indian drug Bdenza, like the analogue drug, has a number of contraindications:

not used to treat women;

not used in pediatrics (up to 18 years of age);
with hypersensitivity (allergy) to any of the constituent components;
severe liver failure.
 

Adverse reactions when using Bdenza
 

The most common side effects when taking Bdenza is fatigue, observed in 30% of treated patients. Less commonly, negative reactions are detected, such as:

pain in the joints, back or muscles;
swelling of the lower and upper extremities;
diarrhea;
dizziness, or frequent headaches;
hot flashes (hot flashes);
sore throat or bronchi.
This symptomatology is observed in 10 to 29% of people.

Fewer than 10% experience increased blood pressure, weight loss, and an apparent loss of stability, which can sometimes lead to injury.

If there is severe pain in the lumbar spine, numbness of the limbs or weakness in the lower half of the body, as well as uncontrolled urination, therapy is stopped.

Due to possible fainting, during the period of treatment it is better to limit driving a car, as well as performing work associated with increased concentration.

 

special instructions
 

From the beginning of treatment, doctors recommend:

drink at least 2 - 3 liters of liquid per day;
if hot flashes occur, you need to change into lighter clothes and apply a cool towel to your head;
avoid traumatic situations in order to avoid damage to the skin;
reduce alcohol consumption to a minimum;
establish proper nutrition;
maintain hygiene, wash your hands more often with soap, this will reduce the risk of infection in the body;
exercise moderately.
Packaging
The package contains 4 plates of 28 capsules (112 pcs). BDENZA Xtandi instructions are attached.

Where and how to buy Enzalutamide Indian drugs

The largest selection of quality anticancer drugs, as well as many other Indian generics in the city of India, is located on the India-Express portal.

If you urgently need to buy Xtandi online or any other cancer drugs on our website at a low price, this can be done without any problems. Place an order, the manager will contact you to confirm the shipping address, and the medicines will be delivered promptly.

All our products are purchased directly from the manufacturer, the quality assurance is confirmed by certificates.